Current Research Projects Modulation of STAT3 activity by STAT5 in triple negative breast cancer Targeting PRMT5 to combat cancer drug resistance associated with neuroendocrine differentiation Current Pilot Projects Decoding Function, Dysfunction, and Dynamic Structure in Ion Signaling Pathways Continuous Real-time Monitoring of Extracellular Glutamate Dynamics in Brain Current Supplement Project Team Science Supplement W. . Past Research Projects Proangiogenic Microstructured Hydrogels for Chronic Wound Treatment - cAMP Signaling in Neuronal Primary Cillia - . Design Principles of Microporous Polymeric Scaffolds for Material-Tissue Integration - Development of a Point-of-Care Metabolomic Diagnostic Sensor Towards Identification of Major Depressive Disorder - Implantable Sensor Array for In Vivo Real-Time Monitoring of Multiple Neurotransmitters - Neural Pathways Underlying Learning with Nicotine Stimulus - The critical role of bromodomain proteins TgBDP1 and TgBDP2 in regulating gene expression in the protozoan parasite Toxoplasma gondii - TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responses - Past Pilot Projects Biological DNA based cellular scaffolds - Characterization of the gut microbiota-gut-brain axis in adult Bhutanese adults - Cryopreservation utilizing antifreeze proteins and polymers - . & Defining heroin use phenotype - Development of Gdf-1 as a Ceramide-Regulating Therapeutic for Acute Myeloid Leukemia - Brian Barth, Ph.D. Engineering Pro-angiogenic Biomaterials with Defined Microstructures and Micromechanics to Enhance Wound Healing - Investigation of an Elastin-Like Polymer Sensing Paradigm for Interleukin-2 - Multiscale computational approaches for allosteric targeting of signaling receptors - . Probing the synergistic effect of inhibitor binding to multiple sites on signaling proteins - & Role of GLI3 in mediating innate immunity - Role of STAT3 in Advanced Ovarian Cancer - The essential bromodomain proteins TgBDP1 and TgBDP2 regulate transcription in Toxoplasma gondii - The role of PRMT5 in DNA damage repair and alternative RNA splicing regulation in Merkel cell carcinoma - Toward the inhibitor-bound structures of Regulators of G-protein Signaling Proteins - . & Past Supplement Projects SARS-CoV-2 whole genome sequencing from large-scale campus testing and state-wide communities in NH - Targeting STAT3 in Ovarian Cancer -
