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• Specific Aims (1 page)
• Research Strategy (4 pages maximum) following these instructions:
  • The RPL should describe long-term goals and delineate the design principles supporting the research or the hypotheses to be tested. Preliminary studies are not required for COBRE Research Projects, but they are encouraged. In the absence of preliminary results, applicants should describe the strengths and weaknesses in the rigor of the prior research (both published and unpublished) that serve as the key support for the proposed project. The Research Strategy should also critically assess the existing knowledge and approaches that have been or are being directed in the area with a specific emphasis on how the anticipated results will advance the field. Moreover, the importance and health relevance of the proposed research should be concisely stated. Each research project should describe its relationship to the COBRE's scientific theme and how the Research Core(s) will be useful to the project.
  • It may be useful (but not required) to divide the Research Strategy into specific sections on Significance, Innovation, and Approach.
  • If you have a previous submission to NIH that was declined, you are welcome to incorporate reviewers’ suggestions into a revised proposal whose aims are scaled to be accomplished within an ~2-year time frame.
• Budget using the UNH Excel budget template file along with the budget justification document. Please review Budget Guidelines section below.
• Appendix
  • Use of human embryonic stem cells? (Y/N)
  • Are human subjects involved? (Y/N)
  • Are vertebrate animals used? (Y/N)   
  • If you do not have and External Scientific Mentor (ESM), identify one or more senior-level researchers who are competent to serve as an ESM (you do not need to seek their participation unless you are selected to be appointed as an RPL).  

Additional considerations:

• If there are changes to your Biographical Sketch since submission of your pre-proposal, please include an updated Biographical Sketch.  
• The scope of the proposed research should be able to be accomplished in a 2-year period and with an annual direct cost budget of $125,000.  
• You will need to be able to commit 6 person-months annually to the project (3 summer months, and 3 AY months). The CIBBR PI will solicit a letter of institutional support (including this effort commitment) from your College Dean and Chair if you are selected.  

Application Form Link -- Solicitation period has closed

Please be prepared to upload your pre-proposal components as a single PDF file.

Deadline: December 1, 2025

All pre-proposals and full proposals from eligible faculty will be reviewed and assigned a priority score by the CIBBR Leadership Team (including ad hoc reviewers as appropriate).

Proposals will be evaluated on the following criteria, following the NIH scoring model (1=Exceptional to 9=Poor)

• Scientific Merit
• Relevance to CIBBR mission
• Potential for candidate achieving R01/R35 funding within 2-3 years
• Vision for the research to evolve with translation and clinical outcomes