National Institutes of Health (NIH) Specific Requirements & Advice

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(NOT-OD-26-004; 10/1/2025)

 

On this page:

 


This page serves as a central location for information about changes impacting NIH grants process and plans for implementing new initiatives and policies.

Highlights:

  • Improving the Safety and Security of Biological Research ()
  • Automatic Early Stage Investigator (ESI) Eligibility Extension ()
  • Supporting Fairness and Originality in NIH Research Applications ().
    • NIH will not consider applications that are either substantially developed by AI, or contain sections substantially developed by AI, to be original ideas of applicants
    • NIH will only accept six new, renewal, resubmission, or revision applications from an individual Principal Investigator/Program Director or Multiple Principal Investigator for all council rounds in a calendar year.
  • Revision: NIH Policy and Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research ()
    • The revised Policy is now titled, "NIH Policy and Guidelines on the Inclusion of Women and Members of Racial and/or Ethnic Minority Groups in Clinical Research."
  • New Policy Requirement to Train Senior/Key Personnel on Other Support Disclosure Requirements ()
  • Preview of NIH Common Forms for Biographical Sketch and Current and Pending (Other) Support Coming Soon to SciENcv ()

 

Changes Implemented for Due Dates on or after January 25, 2025

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-- slides and video


An infographic from the Center for Scientific Review to help clarify the process that highlights institution- and investigator-specific information, including key actions that must be taken well in advance of application submission


Policy Considerations and Guidance re: Research Participant Protections; Data Management and Sharing; Health Information Privacy; Licensing, Intellectual Property, & Technology Transfer; Peer Review; and Biosecurity and Biosafety PLUS additional resources for researchers
   See also: Supporting Fairness and Originality in NIH Research Applications

 

Researchers can use the NIH-specific filters in this search tool to quickly identify potential funding opportunities of interest in . 
> Starting in October 2025, Grants.gov is the single official source for NIH grant opportunities. 
    Use for notifications of new opportunities. 
>

(For Unsolicited or Investigator-Initiated Applications)




for use with Institutional Research Training grant applications, etc.

  
   : Preview of NIH Common Forms for Biographical Sketch and Current and Pending (Other) Support 
   Coming Soon to SciENcv

Note: 
> All Senior/Key Personnel listed on the R&R Profile form must have an eRA Commons ID
> All Senior/Key Personnel listed on the R&R Profile form need to have an ORCID ID linked to their eRA Commons account to use the new Common Forms for Biosketch 
 

 


 


 


 

 

 

NIH ADVICE




Videos, slides, and transcripts from conference and pre-conference presentations

 

- a tool to recommend a potentially appropriate study section

    - infographic
    - video
 
    A ”one-stop explanation of the core values of peer review and the NIH policies that uphold them”

   

   

 


This comprehensive guide covers all aspects of seeking funding: finding opportunities, interacting with NIH, application preparation, review, and more.
Includes

 

 

For other resources, see  RD Digital Library >> NIH -- National Institutes of Health

 

 

 

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